{"id":25591,"date":"2025-12-23T10:34:37","date_gmt":"2025-12-23T10:34:37","guid":{"rendered":"https:\/\/essorage.fr\/products\/lyophilization-equipment\/"},"modified":"2026-02-11T10:57:23","modified_gmt":"2026-02-11T10:57:23","slug":"lyophilization-equipment","status":"publish","type":"page","link":"https:\/\/essorage.fr\/en\/products\/lyophilization-equipment\/","title":{"rendered":"Lyophilization Equipment"},"content":{"rendered":"\t\t
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Conventional lyophilizers are referred to as <\/span>static<\/b> because the product to be lyophilized is placed in vials, flasks, trays, or other containers that do not move during the lyophilization cycle.<\/span> <\/p>

Temperature decrease\/increase is regulated by the refrigeration system, which cools\/heats the thermofluid (silicone oil type) circulating in the shelves where the samples are placed. <\/span><\/p>

The <\/span>dynamic<\/b> lyophilization technology developed by LYOPHITECH<\/a> decouples the freezing and sublimation steps in an oscillating drum, resulting in a high-quality product in the form of <\/span>beads<\/b> (1 to 5 mm).<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Static Lyophilizer<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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Depending on your needs: R&D, Pilot, Production, standard finish, pharma quality, sterile environment, as well as your budget, we can guide you towards the right model.<\/span><\/p>

Our partners do not manufacture in China.<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t

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Dynamic Lyophilizer<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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OPE represents <\/span>LYOPHITECH<\/b><\/a> in Belgium.<\/span><\/p>

Their patented technology is particularly suitable for <\/span>oxygen-sensitive products and living products<\/b> (Probiotics, LBPs\u2026), as it combines flash freezing in liquid nitrogen, which prevents the generation of large crystals, with gentle lyophilization controlled by pressure.<\/span><\/p>

The beads formed also exhibit microporosity, which greatly facilitates re-dissolution.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\tPLEASE NOTE\n\t\t\t\t\t<\/h6>

Regulations on refrigerants are evolving, our partners<\/span><\/span> have low GWP solutions:
liquid nitrogen, natural gases, or even air in some cases\u2026 Contact us to learn more<\/h3><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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\n\t\t\t\t\t\tDID YOU KNOW?\n\t\t\t\t\t<\/h6>

The lyophilizer<\/span><\/span> you need might be available on the used market?<\/h3><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t
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Feel free to visit www.isayo.fr<\/a> and let us know your needs.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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\n\t\t\t\t\t\t\t\n\t\t\t\t\tVisit the ISAYO website\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n <\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Process Control \u2013 TEMPRIS technology<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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The <\/span>TEMPRIS<\/b><\/a>\u00ae<\/a> technology is the solution for controlling your lyophilization process with precisely measured, real-time, wireless, and battery-free product temperature, compatible with GMP \u2013 Annex 1, in a sterile environment.<\/span><\/p>

The latest options of the <\/span>LyoCLC <\/b>(Lyophilization Closed-Loop Control) software allow you to optimize processes: adjustment of cycle times, data acquisition for perfect scale-up, and facilitation of your process transfers.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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\n\t\t\t\t\t\tDID YOU KNOW?\n\t\t\t\t\t<\/h6>

OPE has been an agent TEMPRIS<\/span><\/span> since 2024 in France and can organize a \u201cretrofit\u201d with the TEMPRIS team on any type of lyophilizer from any brand.<\/h3><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t
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Give a new dimension to your lyophilization processes and facilitate your transfers from R&D to production thanks to data acquired via the LyoCLC option!<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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\n\t\t\t\t\t\t\t\n\t\t\t\t\tContact Us\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n <\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Conventional lyophilizers are referred to as static because the product to be lyophilized is placed in vials, flasks, trays, or other containers that do not move during the lyophilization cycle. Temperature decrease\/increase is regulated by the refrigeration system, which cools\/heats the thermofluid (silicone oil type) circulating in the shelves where the samples are placed. The […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":25581,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-25591","page","type-page","status-publish","hentry"],"yoast_head":"\nLyophilization Equipment - OPE<\/title>\n<meta name=\"description\" content=\"Explore static and dynamic lyophilizers tailored to your R&D, production, and pharma quality needs. 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